What is Plasmapheresis DFPP? A new option for toxin removal and vascular care.

In the modern era, as lifestyles evolve, the risk of developing various diseases—such as cerebrovascular and cardiovascular diseases, hyperlipidemia (high cholesterol), diabetes, and hypertension—is on the rise. This increase is attributed to the accumulation of toxins, fats, and inflammatory agents in the body, originating from factors like diet, daily pollution, lack of exercise, chronic stress, and insufficient rest.

Vascular health innovations like Plasmapheresis DFPP, or Double Filtration Plasmapheresis (a two-step plasma filtration technology), offer an effective and safe alternative for precise internal health care. This article from LINNA Clinic compiles essential information about DFPP, including its mechanism of action, its benefits, who is suitable for the treatment, its pros and cons, as well as pre- and post-procedure preparation methods, to serve as a guide for decision-making before undergoing the service.

Table of Contents

What is Plasmapheresis?

Plasmapheresis is a process of blood cleansing using a specialized filter to separate plasma from blood cells. It helps reduce the amount of unwanted substances such as bad fats (LDL), triglycerides, abnormal antibodies or immune stimulants, and inflammatory proteins. The clean plasma is then returned to the body. This process results in cleaner blood while helping to balance the body’s immune system.

Popular forms of Plasmapheresis can be divided into two types:

  • Conventional Plasmapheresis (Therapeutic Plasma Exchange: TPE): This involves filtering and separating plasma from the blood and replacing it with plasma from a donor or a replacement solution.

  • Double Filtration Plasmapheresis (DFPP): This uses a two-layer filtration process to eliminate as many unwanted substances as possible, resulting in cleaner and smaller-molecule plasma. This clean plasma, along with blood cells and other essential components, is then returned to the body without the need for external replacement solutions.

What is the technique for performing DFPP?

Double Filtration Plasmapheresis, or DFPP, is a Plasmapheresis technique that uses a two-step plasma filtration process. The first filtration layer separates the plasma from the blood cells. The resulting plasma is then passed through another specialized filter to selectively separate and remove unwanted foreign substances, such as fats, viruses, allergens, abnormal antibodies, or proteins related to inflammation. The clean plasma, along with blood cells and other essential proteins, is then returned to the body.

Blood purification using the DFPP technique thus helps minimize the loss of important proteins and prevents risks associated with using replacement plasma.

DFPP procedures can be divided into two types based on the flow rate of the blood and plasma used:

  • Low Flow DFPP: This involves filtering the plasma through a normal-sized vein and does not require the insertion of a large catheter. It can be performed in hospitals or standard clinics and is suitable for individuals seeking to gradually reduce blood lipids or alleviate inflammatory conditions.

  • High Flow DFPP: This involves filtering the plasma using a high blood flow rate to rapidly eliminate abnormal substances or excess fats in the blood. It is suitable for individuals with severely high blood lipid levels or severe inflammation who require clear and fast results. Because this procedure involves puncturing a large artery, typically in the neck area, it must be performed only in a hospital setting with complete standard equipment, under the close supervision of experienced medical and nursing teams.

Mechanism of DFPP Action

  1. A doctor draws blood from a designated area and sends it through the Primary Filtration machine to separate the plasma from the cellular components of the blood, which include red blood cells, white blood cells, and platelets.
  2. The separated plasma is then sent to the Secondary Filtration process, which has the capability to selectively filter and remove viruses, waste, fats, toxins, allergens, as well as pro-inflammatory proteins. This results in cleaner plasma with smaller molecules.
  3. The plasma that has gone through the two-step filtration process, blood cells, and other essential proteins are returned to the body without the need for replacement fluid, or using less than is required for conventional blood filtration methods.

What DFPP Helps With

  • Reduces bad fats (LDL) and triglycerides in individuals with abnormal levels.Decreases the amount of antibodies, inflammatory agents, and allergens that trigger autoimmune diseases, multiple sclerosis, or other inflammatory nervous system disorders.
  • Helps reduce blood viscosity, improving blood circulation and lowering the risk of vascular diseases.
  • Eliminates toxins and waste accumulated in the blood that the body cannot fully excrete, leading to cleaner blood.
  • Helps reduce the chance of inflammation in blood vessels and other important organs of the body.

  • Enhances the balance of the body’s immune system and promotes overall health recovery.

Who is DFPP Suitable For?

  • Individuals with hyperlipidemia (high blood fats) who do not respond to lipid-lowering drugs.
  • Individuals with vascular problems, such as narrowed or hardened arteries, blood thickening, or abnormal blood viscosity.
  • Individuals with kidney disease or a history of organ transplantation.
  • Individuals with diabetes.
  • Individuals with abnormally high protein levels in the blood.
  • Individuals with neurological disorders or autoimmune diseases, such as Systemic Lupus Erythematosus (SLE) or Myasthenia Gravis.

  • Individuals seeking holistic health recovery and boosting immune system function.

Who is DFPP Not Suitable For?

  • Individuals with easy bleeding conditions or abnormal blood clotting.
  • Individuals with severe chronic diseases, such as cardiovascular disease or kidney failure.
  • Patients with severe, uncontrolled infections.
  • Individuals with very low blood pressure (hypotension).
  • Pregnant or breastfeeding women, as well as women during menstruation (should be evaluated on a case-by-case basis by a doctor).
  • Individuals with a history of allergy to medications or solutions used in the DFPP procedure.

Advantages of DFPP

  • Uses a two-step filtration system, capable of selectively separating and removing only unwanted substances from the blood efficiently, leading to cleaner blood, reduced inflammation, and a lower risk of chronic diseases.

  • Helps lower blood fat levels, especially LDL and triglycerides, improving blood circulation and preventing the risk of vascular disease, high cholesterol, high blood pressure, and fatty liver disease.

  • Helps balance the immune system, promotes overall body strength, and assists in holistic health recovery.

  • Does not require external replacement plasma or chemicals like conventional blood cleansing, thereby reducing the risk of allergic reactions and other side effects.

Is DFPP Dangerous? What are the Side Effects?

Generally, DFPP is considered highly safe when performed under the supervision of an experienced physician, using clean and standardized equipment. Potential side effects may include low blood pressure (hypotension), headache or dizziness, nausea and vomiting, bruising or swelling at the venipuncture site, or in some cases, numbness around the mouth or hands due to decreased calcium levels in the blood. These symptoms are usually temporary and gradually improve within a few days with proper care as advised by the doctor.

How Often Should DFPP be Performed to See Results?

The frequency of DFPP depends on the disease and the severity of the symptoms. For acute conditions, a doctor may recommend continuous treatment for 1–2 weeks, performing the procedure 2–3 times per week to help reduce the level of pathogens or toxins in the blood. For chronic disease management or health restoration, it may be done 4–6 times over 1–2 months, then reducing the frequency as per the doctor’s discretion. For those doing it for preventive health care without severe underlying diseases, doctors usually recommend doing it 1–2 times per year to help remove waste and maintain good blood flow balance.

However, the patient should understand that DFPP is only a supplementary approach to health recovery and cannot replace primary treatment. Therefore, consultation with an experienced physician is essential to assess suitability and safety before commencing the therapy.

Preparation Before DFPP

  • Undergo a thorough health and blood check-up to evaluate readiness before starting the blood filtration process.

  • Refrain from food and beverages (except plain water) for at least 12 hours, or as recommended by the doctor.

  • Stop using medications or supplements that affect blood clotting as instructed by the doctor.

  • Get sufficient rest and drink enough water.

Self-Care After DFPP

  • Drink plenty of clean water to help stimulate blood circulation and promote body recovery.

  • Eat nutritious food, quit smoking, and avoid alcohol consumption.

  • Get sufficient rest and avoid strenuous activities within the first 24 hours.

  • Take medications prescribed by the doctor and attend follow-up appointments as scheduled.

  • If abnormal symptoms occur, such as severe dizziness, unusual fatigue, severe bruising/swelling, or uncontrollable bleeding, seek immediate medical attention.

Conclusion

DFPP, or Double Filtration Plasmapheresis, is a high-efficiency, two-layer plasma filtration innovation that helps reduce the amount of fats, toxins, accumulated waste, antibodies, and pro-inflammatory proteins, resulting in cleaner blood without the loss of plasma and other essential components like in conventional blood cleansing. It is suitable for individuals with vascular diseases, hyperlipidemia, certain immune conditions, and those seeking holistic health recovery. For optimal and safe results, DFPP should only be performed under the supervision of an experienced physician. If you are interested in consulting about health issues or planning individualized health recovery with the DFPP blood filtration technique, you can contact us at 063-609-8888, Whatsapp +66 919799554, or via LINE: @linnaclinic.

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