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KARISMA RH COLLAGEN

Karisma Rh Collagen is a new innovation in skin care that is now widely talked about. It stands out as the world’s first Collagen Bio-Restitutive, using Recombinant Human Collagen (Rh Collagen) as the main component, which is up to 99.9% similar to human Type I Collagen. It not only helps fill deep wrinkles but also restores the skin from within by simultaneously stimulating collagen production. This makes it a perfect solution for modern skin care needs, creating naturally beautiful skin with visible improvements, fast results, and proven safety.
What is Karisma Rh Collagen? Is it really effective? How is it different from other skin rejuvenation substances? LINNA Clinic has the answers.
What is Karisma Rh Collagen?
Karisma Rh Collagen is the world’s first Collagen Bio-Restitutive (Bio Restorative + Bio Stimulative), with its key component being Recombinant Human Collagen (Rh Collagen). This collagen is synthesized from genetically modified silkworms (Transgenic Silkworm) using TAUMED’s proprietary technology from Italy. Rh Collagen has a molecular structure that is 99.9% identical to human Collagen Type 1, making it highly biocompatible and minimizing the risk of allergic reactions. Its primary function is to stimulate fibroblast cells to continuously produce new collagen.
In addition to Rh Collagen, Karisma Rh Collagen also contains two other essential components:
High Molecular Weight Hyaluronic Acid (HMW-HA), Non-Cross Link: Provides deep hydration, instantly plumping the skin for a natural volumizing effect after injection.
Carboxymethylcellulose (CMC): Enhances the stability of HA, prevents collagen breakdown, and supports long-lasting skin regeneration.
With the synergistic action of these three active ingredients, Karisma Rh Collagen not only fills wrinkles and deep folds immediately similar to conventional fillers but also stimulates natural collagen production for long-term results. The skin becomes firmer, smoother, and more youthful-looking in a natural way. Visible improvements can be seen within 2–4 weeks, and results typically last around 6–12 months, depending on the individual.

What does Karisma Rh Collagen help with?
- Fills deep wrinkles and softens fine lines, such as forehead lines, under-eye wrinkles, nasolabial folds, and marionette lines.
- Stimulates new collagen and elastin production, restoring skin firmness and elasticity.
- Reduces acne scars and other skin imperfections, leaving the skin smoother and more refined.
- Evens out skin tone and enhances radiance.
- Boosts skin hydration, improving dryness and rough texture.
Strengthens the skin’s internal structure, keeping it naturally radiant and healthy for the long term.
Who is Karisma Rh Collagen suitable for?
- People with wrinkles or deep facial lines.
- Those experiencing sagging skin or folds on the face, neck, décolleté, and hands.
- Individuals with scars, acne marks, or enlarged pores.
- People dealing with dry, rough, or dull skin.
Those seeking a safe skin rejuvenation and filling option that minimizes the risk of allergic reactions and delivers naturally youthful-looking results.


Where can Karisma Rh Collagen be injected?
- Forehead: Fills in wrinkles and folds, smoothing the skin.
- Under the eyes: Reduces deep lines and dark circles.
- Sunken cheeks: Restores volume and facial balance for a youthful look.
- Nasolabial folds and marionette lines: Softens deep lines, giving a lifted and younger appearance.
- Lips: Improves dryness and deep lines, adding natural fullness.
- Acne scars and other scars: Stimulates collagen to smooth the skin and fade scars.
- Neck: Reduces wrinkles, folds, and sagging, making the area appear smoother.
- Décolleté: Diminishes wrinkles and sagging in the chest area.
Hands: Fills folds and wrinkles on the back of the hands, restoring a youthful and healthy look.
How many sessions of Karisma Rh Collagen are recommended?
In general, doctors usually recommend 2 initial sessions of Karisma Rh Collagen, spaced about 1 month apart, followed by a 3rd booster injection after 4–8 months. After that, maintenance sessions can be repeated every 6–12 months to sustain long-lasting results. However, the exact number of sessions may vary depending on age, skin condition, and individual response.
How long does Karisma Rh Collagen last?
The results of Karisma Rh Collagen typically last about 6–12 months, depending on skin condition, treatment consistency, and individual aftercare. In some cases, results may last up to 18 months when following the doctor’s recommendations closely.
How is Karisma Rh Collagen different from Sculptra, Radiesse, Juvelook, and Profhilo?
Karisma RH Collagen is a Collagen Bio-Restitutive (Bio Restorative + Bio Stimulative) that not only fills wrinkles and instantly hydrates the skin but also uses Rh Collagen, with a structure up to 99% identical to human Collagen Type 1. This allows for safe, natural collagen stimulation. It is ideal for those seeking holistic skin rejuvenation—plump and hydrated skin immediately, stronger skin structure, and results lasting 6–12 months.
Sculptra belongs to the Collagen Biostimulator group and uses Poly-L-lactic acid (PLLA), which gradually stimulates collagen production. Results are not immediate but become visible after 4–6 weeks. The effects last up to about 24 months, making it suitable for individuals looking for long-term structural skin restoration rather than instant volume.
Radiesse is a Hybrid Biostimulator composed of CMC and Calcium Hydroxylapatite (CaHA) microspheres. It provides both immediate lifting and volumizing effects while also stimulating collagen in the long term (lasting 12–18 months). With its thicker, firmer texture compared to Karisma Rh Collagen, it is best for deeper lifting, facial contouring, or quick volume enhancement.
Juvelook is a Hybrid Biostimulator combining synthetic PDLLA with Hyaluronic Acid (HA). It focuses on hydration, improving superficial skin texture, smoothing acne scars and blemishes, while mildly stimulating collagen. Results can last up to 18 months.
Profhilo is categorized as a Skin Booster, primarily made of highly concentrated Hyaluronic Acid. It excels in hydration, giving the skin a glowing, dewy look with mild collagen stimulation. Results appear within 2–8 weeks and last around 6–8 months. It is most suitable for those seeking radiant, healthy-looking skin rather than deep lifting or structural improvement.
How to take care of yourself before and after Karisma Rh Collagen injections?
Pre-treatment care before Karisma Rh Collagen injection
- Inform your doctor about any underlying conditions, current medications, or history of allergies to evaluate suitability before the procedure.
- Avoid aspirin, NSAIDs, vitamin E, fish oil, and herbal supplements for at least 7 days.
- Refrain from alcohol and smoking for 24–48 hours.
- Avoid other procedures in the intended injection area for at least 2–4 weeks.
- Get sufficient rest (6–8 hours) and stay well-hydrated prior to the treatment.
Post-treatment care after Karisma Rh Collagen injection
- Avoid pressing, massaging, or applying strong pressure on the treated area during the first week. If swelling or bruising occurs, apply a cold compress as advised by your doctor.
- Refrain from facials, treatments, or skincare products with exfoliating agents such as AHA, BHA, Retinol, or Tretinoin for at least 1–2 weeks to prevent irritation, inflammation, or infection.
- Avoid strenuous exercise, facial massage, sauna, or exposure to excessive heat for the first 48 hours.
- Do not consume alcohol or smoke for at least 3–7 days.
- Drink 1.5–2 liters of water daily to support optimal skin recovery.
- Apply moisturizer and sunscreen regularly.
If abnormal swelling, redness, or significant pain occurs, consult your doctor immediately.
Summary
Karisma Rh Collagen is the world’s first Collagen Bio-Restitutive (Bio Restorative + Bio Stimulative) injectable innovation. Its key ingredient, Recombinant Human Collagen (Rh Collagen), is 99.9% structurally identical to human Collagen Type 1. It helps fill deep wrinkles and instantly plump the skin, while also stimulating long-term collagen production from within. The result is firmer, tighter, and naturally youthful-looking skin, with effects lasting 6–12 months.
It is suitable for individuals with skin laxity, wrinkles, deep lines, acne scars, or anyone seeking safe and natural skin rejuvenation.
For consultations or appointments, please contact LINNA Clinic at 063-609-8888, WhatsApp: +66 919799554, or LINE: @linnaclinic.





