In an era where beautiful skin is no longer defined solely by fairness or radiance, but by deep, multidimensional skin health, HarmonyCa™ has emerged as an innovative solution that addresses comprehensive skin concerns in a single treatment.
This advanced injectable combines two powerful ingredients:
Hyaluronic Acid (HA) – which instantly hydrates the skin and smooths out fine lines, and
Calcium Hydroxyapatite (CaHA) – which stimulates natural collagen production for long-term lifting and elasticity.
With its unique dual-action formula that both fills and regenerates the skin structure, HarmonyCa™ has become one of the most talked-about and popular dermal fillers today.
What is HarmonyCa™? What can it help with? Who is it suitable for? And is it safe?
This article from LINNA Clinic has all the answers.
Table of Contents
What is HarmonyCa?
HarmonyCa™ is a hybrid dermal filler that combines the benefits of Hyaluronic Acid (HA) and Calcium Hydroxyapatite (CaHA) in a single formulation. It is developed by Allergan Aesthetics, a leading aesthetics company from the United States and the maker of the globally renowned Juvederm® fillers.
The two key components work in synergy:
Hyaluronic Acid (HA) instantly hydrates the skin, smooths fine lines, and restores plumpness, leaving the skin soft, refined, and visibly rejuvenated.
Calcium Hydroxyapatite (CaHA) gradually stimulates the body’s natural collagen production beneath the skin, resulting in firmer, more elastic, and youthful-looking skin over time.
The outcome is a naturally lifted, refreshed appearance with visible anti-aging effects. Results typically last between 12 to 18 months, depending on individual factors such as age, skin condition, and lifestyle.
Benefits of HarmonyCa
- Restores skin structure by increasing hydration and stimulating collagen production beneath the skin, resulting in stronger skin structure, improved elasticity, firmness, and long-term reduction of skin sagging.
- Reduces wrinkles and fills deep lines. With its ability to add volume quickly through HA, it helps the skin appear smoother and more youthful.
- Increases skin hydration, making the skin plump, radiant, and healthy from within.
- Naturally enhances facial contours by restoring volume in areas such as nasolabial folds, jawline, and cheekbones, helping the face look more balanced and aesthetically pleasing.
How Does HarmonyCa Work?
HarmonyCa is a hybrid dermal filler that works through the combined action of two key ingredients: Hyaluronic Acid (HA) and Calcium Hydroxyapatite (CaHA), delivering both immediate and long-term skin rejuvenation effects:
- When injected into the skin, HA helps restore volume and structure in areas affected by aging and dehydration. It instantly hydrates the skin, making it appear plumper, more contoured, and reducing the appearance of fine lines and wrinkles — giving the face a more youthful look right after treatment.
- Meanwhile, the CaHA particles gradually stimulate the body’s natural collagen production beneath the skin. Over time, this leads to improved firmness, elasticity, and long-term skin regeneration.
Additionally, HarmonyCa contains Lidocaine, a local anesthetic, to help minimize discomfort during the injection process and make the treatment experience more comfortable.
Who is HArmonyCa suitable for?
- Individuals experiencing wrinkles, deep facial lines, and sagging skin caused by the natural decline of collagen and elastin with age.
- People seeking facial lifting and contouring without surgery and with no downtime.
- Anyone looking for a comprehensive solution that both fills and rejuvenates the skin structure in a single session saving time and aesthetic costs.
- Those with known allergies to any components of the product, such as Lidocaine or Hyaluronic Acid (HA)
Who is not suitable for HarmonyCa?
- Pregnant or breastfeeding individuals
- Those with certain medical conditions, such as autoimmune disorders or blood clotting issues
- Individuals with active skin conditions like acne or dermatitis (treatment should be postponed until the condition is resolved)
- Those with known allergies to any components of the product, such as Lidocaine or Hyaluronic Acid (HA)
Before receiving HarmonyCa injections, it is essential to consult with a qualified physician and inform them of any health conditions, current medications, or allergy history to ensure safety and appropriate treatment planning.
How often should HarmonyCa™ be injected?
Since HarmonyCa is a hybrid filler that delivers both immediate and long-term results, its effects typically last 12–18 months, depending on skin condition and lifestyle.
After that period, doctors may recommend a maintenance treatment every 18–24 months to sustain optimal skin rejuvenation results.
How long does HarmonyCa last?
HarmonyCa offers long-lasting results, generally lasting 12–18 months, depending on factors such as age, skin condition, and post-treatment care.
You will see immediate improvements in skin plumpness and volume, with the full rejuvenation effects becoming more noticeable after 3–6 months, as collagen and elastin production increases — leading to smoother, firmer, and naturally lifted skin.
Is HarmonyCa safe?
HarmonyCa is a US-FDA approved hybrid filler, also approved by the Thai FDA, and widely recognized in the global medical aesthetics field.
Its main components, HA and CaHA, are biocompatible substances that naturally exist in the body, making them safe and well-tolerated.
To ensure safety, it is crucial to receive treatment from an experienced physician using authentic products with verifiable sources.
How to prepare before a HarmonyCa injection
- Avoid alcohol, dietary supplements, and medications that affect blood clotting (e.g., NSAIDs, aspirin, vitamin E, fish oil) for at least 1 week before the procedure
- Inform your doctor about any existing medical conditions, current medications, or allergies
- Get at least 6–7 hours of sleep the night before and drink plenty of water to optimize treatment effectiveness
- If you are feeling unwell (e.g., with a cold or inflamed skin in the target area), inform the clinic and postpone the appointment until you are fully recovered
Post-treatment care for HarmonyCa
- Avoid touching, pressing, or massaging the treated area to prevent inflammation or irritation
- Do not apply makeup for 24 hours post-treatment to reduce the risk of chemical-induced irritation
- Drink plenty of clean water to help activate HA and maintain naturally dewy, hydrated skin
- Apply sunscreen daily with high SPF to protect the skin from UV-induced irritation or discoloration
- Avoid intense exercise or facial blood circulation-stimulating activities for at least 48 hours
- Refrain from alcohol consumption and smoking for at least 1 week to support full recovery and minimize potential side effects
Conclusion:
HarmonyCa is a hybrid dermal filler that combines the skin-plumping benefits of Hyaluronic Acid (HA) with the long-term regenerative effects of Calcium Hydroxyapatite (CaHA). It effectively addresses wrinkles, deep lines, and skin laxity while stimulating natural collagen production for firmer, more elastic skin.
With results lasting up to 12–18 months, HarmonyCa is a highly safe treatment, certified by the US FDA and Thai FDA. It is ideal for those seeking a natural, youthful appearance with long-lasting effects.
If you’re interested in rejuvenating your skin with HarmonyCa, consult with our experienced physicians at LINNA Clinic, whatsapp +66 919799554